Ketamine Treatment Center for Depression | PTSD Fairfax, Virginia | 703-844-0184

Recover from Depression and Pain |NOVA Health Recovery Ketamine Treatment Center 

Northern Virginia’s Top Provider of Ketamine

We use Ketamine to treat the following disorders:

Depression

Suicidal Thoughts

Post-Partum Depression

Anhedonia (low mood)

Anxiety Disorders

Bipolar Disorder

Migraine Headache

Fibromyalgia

CRPS| RSD

PTSD

Obsessive Compulsive Disorder

Lyme Disease

 Who Should have Ketamine therapy?

If you have tried numerous therapies including medication, TMS (transcranial magnetic stimulation), or even ECT, ketamine may be right for you. Even if you want to consider ketamine to boost your current treatment outcomes or minimize your medications, consider this treatment option. For CRPS and pain syndromes, Ketamine has been extremely helpful as add-on therapy.

What is ketamine?

Ketamine is a medical agent used for over 50 years as an anesthetic agent in surgery and sedation. It has a proven safety record and was even utilized on the battle fields during the Vietnam War to transport patients off the field. In the Emergency Department it has been an effective medication for procedural sedation, allowing the patient to maintain all their vital signs and breathing even at high doses.  The side effect profile is very low when monitored appropriately. In the early 2000’s , the anti-depressant properties of Ketamine were more formerly evaluated, with Carlos Zarate, the Chief of Neurobiology at the National Institute of Mental Health, characterized the positive impact of ketamine in the successful therapy of Treatment Resistant Depression. This was showcased in a  JAMA 2017 Interview Article { https://jamanetwork.com/journals/jama/article-abstract/2662752 } in which he describes the effective use of ketamine in mood disorders that other treatments had failed to relieve.

How is Ketamine Administered?

Dr. Sendi uses precision-medicine to treat each condition and evidenced based plans to maximize outcomes. Each disorder has a different protocol which can be discussed in consultation. Generally, the depression treatment will be a series of 6 infusions over 2-3 weeks, with the decision of continuation based on the improvement rated after the second infusion. For PTSD, Dr. Sendi uses a two infusion approach a week apart. Pain management may require higher dosing over several hours.

  • IV infusions of Ketamine over 45 minutes for depression and mood related disorders
  • IV Infusions of Ketamine for Pain | CRPS, generally over several hours at a setting.
  • Nebulized Ketamine for patients with a fear of needles
  • Intranasal Ketamine for follow up home treatments after completion of initial treatment
  • Periodic infusions as needed for patients with breakthrough symptoms
  • Oral Troches (lozenges) of Ketamine with additional treatment for some depressive and anxiety states.
  • Trigger point injections offered for fibromyalgia and pain management infusions of Ketamine
  • IV High dose Vitamin therapy offered as an add-on to Ketamine treatments for the benefit of boosting energy, mood, and health. This includes high dose Vitamin C, B-complex, methyl-cobalamins,Magnesium, calcium, zinc and trace minerals that are frequently low in pain states, mood disorders, addiction, and excess weight.
  • Ketamine with NAD therapy for addiction treatment including alcohol and opioid use disorders.

What are the success rates in treatment?

For depression treatment, Dr. Sendi sees more than a 50% improvement in 85% of the patient, most of whom have had limited success on multiple other medications and treatments. For CRPS, this is a treatment of choice.

How Fast are the results?

Ketamine is a rapidly acting anti-depressant, with patients showing improvement of mood within the first 24 hours. Suicidal thoughts can be diminished within hours after the first infusion. Results for responders is within days. We use the Beck Depression Inventory score to assess response for our patients within depression so we can get a consistent scoring of improvement to pass on to your therapist.

How Long do results Last?

Outcomes are variable for length of results, but in our experience, patient with continued psychiatric and medical care can have excellent responses for several months before needing any further treatments. We do provide intranasal ketamine prescriptions for selected patients to extend responses even longer

What does Ketamine therapy feel like?

The experience most patients have during treatment is a mood-elevating state that is generally pleasant. Insightful thoughts and understanding of complex problems are frequently gained by many patients as they focus on internal turmoil. Some patient will bring their therapist to work out solutions to their problems. Others will focus on evocative musical scores that guide them through the experience. Guided imagery with the assistance of a therapist is an option for treatment for many patients as this helps them cope with and understand problems they may be facing. For some patients, they have described vivid dreams which they can control, while others have had a synesthetic experience in which they can hear colors and see sounds. You will be awake for the infusion, which is generally a lower dose for mood disorders. You are in control of the infusion and can stop it at any time.  Every infusion is a different experience, and for some patients, there can be some dysphoria (bad feelings) during the infusion. These experiences do not impact the outcome of treatment, but rather we look for the mood alterations as studies have demonstrated better outcomes in patients who get mood elevations during the infusion.

Are There side Effects of Ketamine?

During the infusion, some patient can have bad dreams, nausea, vomiting, and dizziness. Some can get anxious during higher doses, which can be adjusted immediately. We provide anti-nausea medications and even sedatives for maximum comfort. After the infusion, you will be unable to drive for 8 hours as your motor skills will be impaired.

Is Ketamine addictive?

Ketamine has been abused, primarily in Southeast Asia, but it is very rare in the United States for this situation. If anything, we primarily see tolerance to the effects of ketamine with few withdrawal symptoms in that population. As far as medical uses of ketamine, the dosing is low and with minimal risk of addiction. In fact, there are studies demonstrating effectiveness in Ketamine for cocaine, heroin, and alcohol addiction. These protocols are available in NOVA Health Recovery for selected patients.

How do I prepare for my infusion?

We request that you have someone drive you to and from the appointment on the day of the infusion. You will be unable to drive for 8 hours after the appointment. Bring a headset and music of your choice on your iphone/android/ipad, but it is best to play evocative, calming music during the infusion. Music that reminds you of happy, special times can be helpful in guiding your experience. Don’t eat any food for two hours before the infusion,but water is fine to drink. We provide bottles of water at the office during the infusion. Be relaxed. The experience is controlled by you and doses can be adjusted to comfort.

Do you use Ketamine Psychotherapy?

If you have a therapist who can come to the office during your infusion, that would be fine to have them provide guided imagery or therapy during a session.  Many patients open up to discussion and insight during infusions and the experience can result in much psychological gain.

Do you provide further therapy and medication support?

For patients without active psychiatric providers, we can connect you with available counselors, for CBT, DBT, and other therapies. I can initiate anti-depressants and other aids in the office, but generally with the continuing care of a mental health counselor. For other patients, we will work closely with your psychiatrist to keep them informed of your progress. As mentioned earlier, Dr. Sendi can offer guidance on dietary choices that impact your mental health and well-being. The choices can be based off pharmacogenomics and nutrigenomic studies and advanced lab testing (hormones,inflammatory markers, advanced lipid and cardiac panels, vitamin levels) that can direct us in nutritional and vitamin supplementation that can allow you to maintain wellness and produce the necessary serotonin and dopamine that drives your mood and memory. We do provide IV Vitamin support for chronic diseases,mental health, addiction, cancer, weight loss, auto-immunity, hair loss, and other conditions. We prefer to look into root causes of your medical condition and not just the symptoms.

What to do with your other treatments:

We will work closely with your therapists. We recommend that you have continued psychiatric visits as before and continue your other medications as before. In fact, the optimal time to make changes in your therapy may be during your period of infusion. Do this on consultation with your therapist. There are few drug interactions with ketamine, but we will need a full list of your medications, allergies, and medical history. 

Ketamine for Depression

 Depression is the Ieading cause of disability in people between the ages of 15 –44. Major depression is a common debilitating disorder affecting 10%–15% of the population per year. Despite advances in the understanding of the psychopharmacology and biomarkers of major depression and the introduction of several novel classes of antidepressants, only 60%–70% of patients with depression respond to antidepressant therapy. Of those who do not respond, 10%–30% exhibit treatment-resistant symptoms coupled with difficulties in social and occupational function, decline of physical health, suicidal thoughts, and increased health care utilization.  According to the findings from the Sequenced Treatment Alternatives to Relieve Depression(STAR*D) study, 50%–66% of patients with depression do not recover fully on an antidepressant medication and one-third of patients do have a remission of their depressive symptoms.

Scientiststhink that in people with clinical depression, certain neurotransmitters may beout of balance. One option for treating depression is prescription drugs that affect the levels of certain chemicals that brain cells use to communicate,called neurotransmitters. These options are sometimes called antidepressant medications. Some types of antidepressant medications that are available include selective serotonin reuptake inhibitors (SSRIs), serotoninnorepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs),and monoamine oxidase inhibitors (MAOIs). These medications affect levels of serotonin, among other neurotransmitters to produce their effect. Other optionsf or treatment include psychotherapy, Transcranial Magnetic Stimulation (TMS),and ECT (Electroconvulsive therapy) .

Despite these advances, many therapies do not work well in a significant percentage of the population and produce their effectiveness very slowly.  In a landmark 2000 study published in Biological Psychiatry (https://doi.org/10.1016/S0006-3223(99)00230-9),Robert Berman and colleagues at the Yale School of Medicine demonstrated that ketamine had quick-action anti-depressant properties on people with treatment-resistant depression. Further investigations by Carlos Zarate (ArchGen Psychiatry. 2006;63(8):856-864. doi:10.1001/archpsyc.63.8.856  : A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression] a single infusion of Ketamine produced robust improvement in depression in 71% of the test subjects and remission in 29%. Further work by Carlos Zarate using Ketamine was showcased in the JAMA 2017 article   [JAMA. 2017;318(20):1964-1966.doi:10.1001/jama.2017.12975 Ketamine Minus the Trip: New Hope forTreatment-Resistant Depression] in which the Ketamine experience of rapid anti-depressant effects was reviewed in an interview.

Ketamine has produced rapid reductions in depression in treatment refractory patients in numerous studies and has performed well when other interventions had minimal impact. This has been experienced in our ketamine center as well. Link to the following articles for more information.

Ketamine in the Media:

KETAMINE RESTORES ABILITY TO EXPERIENCE PLEASURE IN DEPRESSED PATIENTS WITHIN MINUTES Newsweek

Ketamine-Induced Optimism: New Hope for the Development of Rapid-Acting Antidepressants Psychiatric Times

Ketamine: from drug of abuse to anti-depressant. The Brain Bank

From Club to Clinic: Physicians Push Off-Label Ketamine as Rapid Depression Treatment [Part 1] Scientific American

Is Ketamine Right for You? Off-Label Prescriptions for Depression Pick Up in Small Clinics, [Part 2] Scientific American

Ketamine, A Darling of the Club Scene, Inspires Development of Next-Generation Antidepressants, Part 3 Scientific American

Ketamine For Severe Depression: ‘How Do You Not Offer This Drug To People?’   NPR

Once It Fully Catches On, Ketamine Could Be a Really Important Antidepressant   New York Magazine

New Hope For Depression Time 2017

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment resistant depression.

Intravenous Ketamine for Adolescents with Treatment-Resistant Depression: An Open-Label Study.

“Ketamine for Depression: The Most Important Advance in Field in 50 Years?” –by Maia Szalavitz, October 5, 2012, TIME

“Party Drug Ketamine Could Help Treat Severe Depression, Says Yet Another Study”–by Dominique Mosbergen, April 5, 2014, The Huffington Post

“Ketamine Could Treat Depression – Illegal Drugs Do Have Their Uses” –by Sue Blackmore, April 4, 2014, The Guardian

“A Dry Pipeline for Psychiatric Drugs”–by Richard A. Friedman, MD, August 19, 2013, The New York Times

“Ketamine ‘Exciting’ Depression Therapy”-by James Gallagher, April 2, 2014, The BBC

“Drug ‘Treats Depression in Hours’ -August 7, 2006, The BBC

“Antidepressant Ketamine May Be More Effective Than Electroconvulsive Therapy”-by Dr. Keith Ablow, February 24, 2014, Fox News

“Ketamine May Help Treat Severe Depression, Reduce Suicidal Urges, UAB Researchers Say”-March 27, 2013, Medical News

“Ketamine Encourages Nerve Remodeling”-by Jef Akst, October 16, 2012, The Scientist

“More Data Supports ‘Special K’ Drug as Treatment for Depression”-by Dr. Keith Ablow, October 19, 2012, Fox News

Is ketamine the best hope for curing major depression?” by Caroline Winter, August 19, 2015, Bloomberg Business

“Ketamine: Can this party drug cure severe depression overnight?” SBS Australia, April 6, 2016, SBS Australia

“Could ketamine become the next great depression drug?” by Timothy Bella, February 12, 2015, Al Jazeera America

“How Ketamine is Treating Mental Illness” by Sarah Jacoby, March 21, 2015, Refinery 29

“Rave Drug “Special K” Holds Promise for Treating Depression Fast” by Sara Reardon, Nature magazine, January 8, 2015, Scientific American

“Street Drug ‘Special K’ May Help Depression” by ABC News, February 4, 2013, ABC 7 Chicago Eyewitness News

Is Ketamine The Next Big Depression Drug?” by Simone Grimm, Milan Scheidegger , May 1, 2013, Scientific American

Ketamine may be quick, effective treatment for untreatable depression” by Michelle Castillo, May 20, 2013, CBS News

“How An Unlikely Drug Helps Some Children Consumed By Fear” by John Hamilton March 25, 2013, Morning Edition, NPR

“Ketamine Effective At Treating Depression” by Joseph Nordqvist, June 4 2013, Medical News Today

“Ketamine Works in OCD, Stubborn Depression” by SkepticalScalpel, May 21, 2013, Physicians Weekly

“Ketamine Relieves Depression by Restoring Brain Connections” by John Hamilton, October 4, 2012, All Things Considered, NPR

“Ketamine shows significant therapeutic benefit in people with treatment-resistant depression” by ScienceDaily, May 18, 2013, ScienceDaily.

“Why Ketamine Helps Fight Depression” by Emily Singer, August 7, 2007, MIT Technology Review

Ketamina: el fármaco que cura la depresión severa en horas” by La Razon, August 27, 2012, La Razon

¿Anestésico para la depresión? Estudio de Mayo Clinic descubre eficacia de dosis bajas de ketamina” by Emily Hiatt, June 6, 2013, Mayo Clinic

IV Ketamine Rapidly Effective in PTSD by John Gever, April 17, 2014, MedPage Today

“Ketamine Restores Ability to Experience Pleasure in Depressed Patients Within Minutes” by Douglas Main, October 21, 2014, Newsweek

Ketamine Improved Bipolar Depression Within Minutes, Study Suggests” by ScienceDaily, May 30, 2012, ScienceDaily

Maintenance Ketamine Treatment Produces Long-term Recovery from Depression” by Primary Psychiatry, May 21, 2013, Primary Psychiatry

Synaptic Dysfunction in Depression: Potential Therapeutic Targets” by Ronalds S. Dunam, George K. Aghajanian, October 5, 2012, Science Magazine.

Special K, a Hallucinogen, Raises Hopes and Concerns as a Treatment for Depression” by Andrew Pollack, December 9, 2014

Let There Be Light” by Kerri Reeves, Fall 2014, Real Women

Anesthesia drug works on severe depression, but off-label use raises concerns” by The Pulse, December 1 2014, The Pulse.

 “Looking Back at Ketamine Delivers New Results in Treatment-Resistant Depression”  Steven P. Levine, July 8, 2013, HCP Live

“Ketamine-Induced Optimism:  New Hope for the Development of Rapid Acting Antidepressants” by Gerard Sanacora, MD, PhD, July 13, 2012 Psychiatric Times

 “Do No Harm, Unless Doing No Harm Hurts” by Steven P. Levine, September 9, 2013, HCP Live

“The Biggest Breakthrough in Depression Research in 50 Years’ is…Ketamine?” by Lindsay Abrams, October 9, 2012, The Atlantic

“Use and Safety of Ketamine: In Plain Terms” by Juvenile Bipolar Research Foundation

“Replication of Ketamine’s Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial” by Biological Phychiatry, February 02, 2012

“Ketamine May Give ‘Almost Instantaneous’ Relief for Severe Depression” by MedPage Today

“Yale Scientists Explain how Ketamine Vanquishes Depression within Hours” by Yale News

“The current mental health crisis and the coming Ketamine revolution” by Lascap, June 16, 2016, Pascal’s Pensees

Ketamine Advocacy Network Thomas Insel, Director, National Institute of Mental Health

“Ketamine Infusions” by International Research Foundation

“Effects of Ketamine on Precipitated Opiate Withdrawal” by PubMed

Ketamine:From Drug Abuse to Anti-Depressant” by The Brain Bank North West, December 10, 2012

“NIH Trial Drug Rapidly Eased Depression” by Kansas City Infozine, December 13, 2012

“Could A Club Drug Offer ‘Almost Immediate’ Relief From Depression?” by John Hamilton, January 30, 2012

“Ketamine Therapy” by South Lake Psychiatry

“‘Club Drug’ Ketamine May Treat Depression, PTSD, Tinnitus” by Texas A&M University, October 15, 2015

“Depressed? Your doctor might soon prescribe ketamine” by The Guardian

“How to Take Ketamine to Treat Depression, Anxiety and PTSD” by How To Use Psychedelic

Clinical Research

Ketamine for Depression

Sleep Drives Metabolite Clearance from the Adult Brain” by Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Department of Neurosurgery,  Department of Neuroscience and Physiology, Langone Medical Center, October 18, 2013

“Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.”  by Am J Psychiatry, October 7, 2013

“Ketamine as a Novel Antidepressant: From Synapse to Behavior” by PubMed, June 5, 2013

“Serial infusions of low-dose ketamine for major depression.” by PubMed, Febuary 20, 2013

“Neurobiological advances identify novel antidepressant targets” by PubMed, October 12, 2013

“The Role of AMPA Receptor Modulation in the Treatment of Neuropsychiatric Diseases” by May 1, 2009

“Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression” by PubMed, August 15, 2013

“Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder” by JAMA Psychiatry, June 2014

“A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists” by The Royal Society Publishing, July 23, 2012

“NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses” by Nature International Weekly Journal of Science

“Signaling Pathways Underlying the Rapid Antidepressant Actions of Ketamine” by US National Library of Medicine National Institutes of Health, January 1, 2013

“Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression” by James W. Murrough, Andrew M. Perez, Sarah Pillemer, Jessica Stern, Michael K. Parides, Marije aan het Rot, Katherine A. Collins, Sanjay J. Mathew, Dennis S. Charney, and Dan V. Iosifescu, 2012

“Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression” by Marije aan het Rot, Katherine A. Collins, James W. Murrough, Andrew M. Perez, David L. Reich, Dennis S. Charney, and Sanjay J. Mathew

“Glutamate NMDA receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure” by Nanxin Li, Rong-Jian Liu, Jason M. Dwyer, Mounira Banasr, Boyoung Lee, Hyeon Son, Xiao-Yuan Li, George Aghajanian, and Ronald S. Duman, April 15, 2011

“A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression” by Nancy Diazgranados, MD, MS, Lobna Ibrahim, MD, Nancy E. Brutsche, MSN, Andrew Newberg, MD, Phillip Kronstein, MD, Sami Khalife, MD, William A. Kammerer, MD, Zenaide Quezado, MD, David A. Luckenbaugh, MA, Giacomo Salvadore, MD, Rodrigo MachadoVieira, MD, PhD, Husseini K. Manji, MD, FRCPC, and Carlos A. Zarate Jr, MD, August 2010

“Maintenance Ketamine Treatment Produces Long-term Recovery from Depression” by Michael M. Messer, MD, and Irina V. Haller, PhD, MS, 2010

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses” by Anita E. Autry , Megumi Adachi , Elena Nosyreva , Elisa S. Na , Maarten F. Los , Peng-fei Cheng , Ege T. Kavalali & Lisa M. Monteggia.

“Targeting the Glutamatergic System to Treat Major Depressive Disorder” by Daniel C. Mathews, Ioline D. Henter, and Carlos A. Zarate, Jr, July 9, 2012

Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action” by National Institute of Mental Health, October 17, 2014

Ketamine: 50 Years of Modulating the Mind by Linda Li  Fron Hum Neurosci 2016

Ketamine for PTSD

Posttraumatic stress disorder (PTSD) is a chronic and disabling condition arising after exposure to a severe traumatic event,characterized by persistent re experiencing, avoidance, and hyper-arousal symptoms. In the general population, prevalence has been estimated at 7.8%,with higher rates in trauma-exposed populations, particularly among survivors of interpersonal violence. Standard therapies used in depression do not work for PTSD , including selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and other medications. These treatments are associated with significant levels of nonresponse and persistent residual symptoms in the few that do respond. One of the first randomized trialsdemonstrating ketamine’s effectiveness in PTSD was in a study by Dr. Feder inJune 2014 [ Efficacy of Intravenous Ketamine forTreatment of Chronic Posttraumatic Stress Disorder A Randomized Clinical Trial JAMA Psychiatry. 2014;71(6):681-688. doi:10.1001/jamapsychiatry.2014.62  ] The study was designed after the recognition that a medical record review of a large sample of burned service members found a significantly lower prevalence of PTSD among patients who received ketamine during post-trauma surgical procedures than among those who did not. This study demonstrated significant improvements in multiple domains in PTSD symptoms and depression that lasted several weeks and beyond.  Ketamine has been shown torapidly increase the number and function of synaptic connections in the prefrontal cortex, rapidly reversing behavioral and neuronal changes resulting from chronic stress and trauma related memories. This data provided the first randomized, controlled evidence that NMDA receptor modulation could lead to the rapid clinical reduction of core PTSD symptoms in patients with chronic PTSD.

Here are some symptoms of PTSD which you can use to screen you or your family members:

Persistent avoidance of distressing memories, thoughts, or feelings about or closely associated with the traumatic events or of external reminders (i.e., people, places, conversations, activities, objects, situations)

Two or more of the following:

  • inability to remember an important aspect of the traumatic events (not due to head injury, alcohol, or drugs)
  • persistent and exaggerated negative beliefs or expectations about oneself, others, or the world (e.g., “I am bad,” “No one can be trusted,” “The world is completely dangerous”).
  • persistent, distorted blame of self or others about the cause or consequences of the traumatic events
  • persistent fear, horror,anger, guilt, or shame
  • markedly diminished interest or participation in significant activities
  • feelings of detachment o restrangement from others
  • persistent inability to experience positive emotions

Two or more of the following marked changes in arousal and reactivity:

  • irritable or aggressive behavior
  • reckless or self-destructive behavior
  • hypervigilance
  • exaggerated startle response
  • problems with conentration
  • difficulty falling or staying asleep or restless sleep

Also, clinically significant distress or impairment in social, occupational, or other important areas of functioning not attributed to the direct physiological effects of medication,drugs, or alcohol or another medical condition, such as traumatic brain injury.

If you or a loved one is suffering from these symptoms, seek help from a therapist if you have not done so already. Ketamine infusions are an excellent choice to help control your symptoms to gain back your life.

Literature on Ketamine and PTSD:

IV Ketamine Rapidly Effective in PTSD  Medpage Today

Recent Study Shows Ketamine Reduces Symptoms of PTSD The Fix

Ketamine May Help Extinguish Fearful Memories  Dana Foundation

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic

Yale: ‘Magic’ Antidepressant May Hold Promise For PTSD

Ketamine for Obsessive Compulsive Disorder (OCD)

Obsessive-compulsive behaviors, commonly referred to as OCD, begin as incessant thoughts that lead to unstoppable, irrational impulses to do things such as repeatedly wash hands, check locks, and other futile activities used to reduce feelings of anxiety.

Common Symptoms of OCD

• obsessive hygiene or cleanliness
• need for object alignment
• repetition of routine or behavior
• concern of potential damage
• compulsive behaviors or thoughts

Unfortunately, the many medical treatments and psychotherapy interventions fail to improve many of these symptoms leaving patients with little hope and much depression. Ketamine, though its ability to diminish intrusive thoughts,may be a significant game-changing intervention for OCD sufferers while they apply other traditional therapies to their condition.

Ketamine: Fresh hope for the treatment of OCD Stanford Medicine Scope

Ketamine Rapidly Reduces OCD Symptoms Psych Congress

Ketamine Is Showing Early Success With Treating OCD  Tonic

Rapid Resolution of Obsessions After an Infusion of Intravenous Ketamine in a Patient with Treatment-Resistant Obsessive-Compulsive Disorder: A Case Report

Glutamate-Modulating Drugs as a Potential Therapeutic Strategy in Obsessive-Compulsive Disorder

Ketamine for Pain Management

Ketamine has been used for pain control and sedation in the Emergency Department setting for many years. It allows patients to dissociate pain from any emotional content and at higher doses can place patients in the “K-hole” in which they are able to carry out their vital body functions, such as breathing, but are unable to feel any pain or recall it.

Ketamine infusions and topical formulations have been used to treat many painful conditions with excellent success rates where standard pain medications have failed. Patients with Complex Regional Pain Syndrome(CRPS), for example, can respond extremely well to Ketamine infusions.Traditional medication approaches, including opioids, have had much less success in this treatment. Our center has utilized Ketamine for CRPS,neuropathies, fibromyalgia, phantom limb pain, and post-herpetic zoster pain syndromes with much success. We also formulate topical therapies that include Ketamine for painful conditions that follow local nerve damage, such as shingles.

NOVA Health Recovery also continues care with pain management as needed, including trigger point injections, joint injections, and continued medication management as well. Call today for an evaluation of your condition to relieve your suffering. 703-844-0184.

Resources for pain management and Ketamine Treatment:

“Low Doses Of A Common Intravenous Anesthetic May Relieve Debilitating Pain Syndrome” by American RSD Hope

“Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome.” by PubMed US National Library of MedicineNational Institutes of Health, September 5

“Outpatient intravenous ketamine for the treatment of complex regional pain syndrome: a double-blind placebo controlled study.” by PubMed US National Library of MedicineNational Institutes of Health, December 15, 2009

“Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome.” by PubMed US National Library of MedicineNational Institutes of Health, September 2004

“Subanesthetic ketamine infusions for the treatment of children and adolescents with chronic pain: a longitudinal study” by BMC Pediatrics, March 26, 2015

Ketamine for Anxiety and Social Phobia

  • Anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the United States age 18 and older, or 18.1% of the population every year.
  • Anxiety disorders are highly treatable, yet only 36.9% of those suffering receive treatment.
  • People with an anxiety disorder are three to five times more likely to go to the doctor and six times more likely to be hospitalized for psychiatric disorders than those who do not suffer from anxiety disorders.
  • Anxiety disorders develop from a complex set of risk factors, including genetics, brain chemistry,personality, and life events.
  • General Anxiety Disorder affects 6.8 million adults, or 3.1% of the U.S. population, yet only 43.2% are receiving treatment. Women are affected more than men, and GAD often co-occurs with depression.

  The continual suffering from anxiety and social phobias results in lost days at work, less life satisfaction, depression,suicidal thoughts, and addiction in many. Alcohol and opioids can become asocial lubricant allowing one to cope with the struggles of the day-to-day panic attacks and stress. For others, the constant need for medications to treat the disorder that seems to still push through can be disabling.

We have found that Ketamine infusions and treatment with other off-label approaches can help significantly reduce symptoms of anxiety, social phobia,and depression. Periodic infusions can be used to maintain effectiveness after the initial successful therapies. We do like to evaluate patient’s biochemistry and genetic profiles in more integrative ways to suggest nutraceutical and nootropic options to lessen symptoms. In some, home prescriptions of intranasal or oral ketamine with oxytocin has been an effective strategy, while in others,IV vitamin therapies with additional micronutrient treatment has made a significant change in patient’s stress and anxiety. We do investigate methylation issues in your genetics to determine more integrative ways to manage the formation of dopamine (the reward molecule) and serotonin levels(the happiness molecule) that can make you feel better. These same strategies are effective for aiding your sleep patterns as well – insomnia goes hand in hand with anxiety and depression.

Ketamine Treatment and Anxiety | Social phobia resources:

Ketamine Effective as Maintenance Treatment for Anxiety  psych congress April 2018

Glue P, Neehoff SM, Medlicott NJ, Gray A, Kibby G, McNaughton N. Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders. Journal of Psychopharmacology. 2018 March 21;[Epub ahead of print].

Maintenance ketamine may offer alternative for patients with treatment-refractory anxiety disorders. Psychiatric News Alert. March 29, 2018.

Ketamine Effects on EEG during Therapy of Treatment-Resistant Generalized Anxiety and Social Anxiety International Journal of Neuropsychopharmacology 2018

The anti-anxiety effects of ketamine are linked to changes in theta brainwaves  Psy Post 2018


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Next Steps…

Contact Dr. Sendi for an appointment Call to Action Call us at 703-844-0184